A 15 year follow up study from Finland has confirmed previous knowledge that that women who stop HRT experience loss of bone mineral density and increased risk of wrist fracture but has also shown that the longer that HRT has been taken, the less is the bone loss and less is risk of wrist fracture.

Having taken HRT for only 5 years or less did not make any long term difference but HRT use for 10 years or more provided most benefit.

Ref Bone loss and wrist fractures after withdrawal of hormone therapy: The 15 year follow-up of the OSTPRE cohort. Saarelainen J et al. Maturitas 2016;85:49-55