Scientists have discovered 14 gene variants linked to hot flushes, giving hope that it will lead to treatments other than hormone replacement therapy.

These differences in genes affect a receptor in the brain which regulates the release of oestrogen.

This suggests if the genes could be switched off, hot flushes, or ‘hot flashes’ as US researchers call them, could be stopped.

Principal investigator Dr Carolyn Crandall, professor of medicine at the David Geffen School of Medicine at UCLA, said: ‘No previous studies have focused on how variants in women’s genes may be linked with hot flashes, and these results were highly statistically significant.’

Full story: Mail Online, 19 October 2016